Turns out you can play a game of Pathfinder with 3 party members in one room and the DM and the other party member in a room 16,200 kilometres away (or 12,750 if you just go straight through the whole thing).
You’ll need a bunch of hardware on either end and decent network connections, but with two laptops and a PC on one end and two laptops on the other end you can make it work. Running Inkscape for the map, Teamviewer for the connection and Skype for the social interaction, it all works surprisingly well.
The first time we tried it, but certainly not the last. Black Skeletons and Champion Skeletal Archers beware!